A manuscript with pitfalls: does the BioNTech vaccine slow down the virus?

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© JOEL SAGET

Berlin – © www.de24.news

 The  answer to this question is eagerly awaited: Can the corona vaccination contain the pandemic by preventing infections on a larger scale? An unpublished manuscript is now circulating on the BioNTech / Pfizer vaccine that suggests this. But the results are still difficult to interpret. © www.de24.news

 The  most important answers:

💉 Isn’t it known how well the vaccines work?

Yes and no. In fact, there is reliable data for the three vaccines approved in the EU on how well they protect against corona disease. © www.de24.news

 The  active ingredient from BioNTech / Pfizer has efficacy values ​​of more than 90 percent. However, until now it was unclear whether the vaccines only ensure that the disease does not break out or also protect against the infection as such. This is an important difference, because in order to contain the pandemic as quickly as possible, as few people as possible should be infected.

💉 What kind of manuscript is there at the moment?

It is a previously unpublished publication by BioNTech and Pfizer together with the Israeli Ministry of Health. Using Israeli health data from vaccinated and unvaccinated people, it was examined, among other things, how well the active ingredient protects against diseases, but also against infections. It is important to know that the manuscript has neither been published by the company nor in a specialist journal that has been peer-reviewed. It became Israeli journalists of the Internet portal ynet leaked. Neither BioNTech nor the Israeli Ministry of Health wanted to comment.

💉 What does it say in the manuscript?

© www.de24.news

 The  active ingredient is “highly effective” in preventing infections with SARS-CoV-2, the authors write. © www.de24.news

 The y had the data from tens of thousands of positive corona tests in Israel and looked at how many of those infected were vaccinated or not © www.de24.news

 The  result: © www.de24.news

 The  proportion of people with full vaccination protection who tested positive for Corona within a certain period of time was significantly lower than the proportion among those who were not vaccinated Percent.

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💉 Why is this number to be used with caution?

© www.de24.news

 The  results of the study are not as clear-cut as the bare number suggests. © www.de24.news

 The  authors themselves point out that their approach may have led to the effect of vaccination on infections being overestimated. Because in Israel the unvaccinated are tested more often than the vaccinated. For this reason alone, there could have been more positive tests in the unvaccinated group. © www.de24.news

 The  Israeli news portal ynet also writes: “© www.de24.news

 The  Ministry of Health made it clear that the data on effectiveness against infections are the least certain compared to the other data.”

💉 What significance would it have if the risk of infection for vaccinated people were much lower?

© www.de24.news

 The  hope is that those who have been vaccinated will rarely be infected with SARS-CoV-2 and thus not pass on the pathogen. That would help enormously to get the infection situation under control.

💉 When could there be more clarity?

Pfizer and BioNTech have not yet commented on the leaked manuscript version. © www.de24.news

 The  two companies were expected to publish the paper in the coming days. Israel’s Corona commissioner Nachman Asch told the army broadcaster on Sunday that it was still unclear to what extent the corona vaccination would also prevent others from being infected. He hoped to find out more about it in the coming weeks. Other vaccine manufacturers have ongoing studies on the subject.

💉 Which results are still in the study manuscript?

© www.de24.news

 The  investigation confirms once again that the vaccine is very effective in preventing diseases and Covid deaths. © www.de24.news

 The  study also showed that the vaccine also works with the more contagious variant B.1.1.7, which was first detected in the UK. Because at the time of the investigation, four out of five positive tests were due to the variant. (WHAT / dpa)





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manuscript pitfalls BioNTech vaccine slow virus

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