Since the intestine has a significant influence on the immune system, it seems quite conceivable that Covid-19 can attack here too. Because severe courses are often accompanied by an excessive immune reaction, the so-called cytokine storm. A team from the Chinese University of Hong Kong has now been able to determine a connection between the severity of the Covid disease and the influence on the intestinal flora.
Microbiome disturbed even after recovery
For their study, the doctors examined the stool samples from 100 Covid patients. Some of the patients gave multiple stool samples, some even up to 30 days after discharge from the clinic. The team sequenced the DNA contained in the samples – from this the type and relative frequency of the intestinal bacteria can be determined. The examination showed clear differences. Classically, antibiotic treatment can change the microbiome – but the changed intestinal bacteria were also found in patients who had not received antibiotics.
The Covid patients therefore had a higher number of Ruminococcus gnavus, Ruminococcus torques and Bacteroides dorei species. Bifidobacterium adolescentis, Faecalibacterium prausnitzii and Eubacterium rectale, however, were less present. Severe courses appeared to be associated with lower numbers of F. prausnitzii and Bifidobacterium bifidum.
The use of antibiotics was taken into account when evaluating the results.
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Covid19 damages intestinal flora PHARMACY ADHOC