What decides whether a corona course will be bad

0
3


What decides whether a corona course will be difficult

Severe courses are related to genes. Image: keystone

Hospitalized Covid-19 patients show a certain gene variation much more often than people with mild courses. In particular, those affected with a partial or total lack of the NKG2C receptor fall seriously ill, the MedUni Vienna reported on Monday.

“This part of the immune response could therefore also be an important target for drugs that could help prevent severe Covid 19 diseases,” said virologist Elisabeth Puchhammer-Stöckl.

 The  antiviral immune response by natural killer cells (NK cells) is an important step in combating virus replication in the early stages of infection. © www.de24.news The se killer cells have special, activating receptors on their surface. © www.de24.news

 The se include the NKG2C receptor, which communicates with an infected cell via one of its specific surface structures, the HLA-E. This interaction leads to the destruction of the virus-infected cells.

Severe courses in the absence of a receptor

Around four percent of the population lacks the activating receptor NKG2C due to a gene variation, while around 30 percent of the population only partially has the receptor. A research group from the MedUni Center for Virology, headed by Puchhammer-Stöckl, has now shown that especially people with a partial or complete absence of the NKG2C receptor develop severe courses.

© www.de24.news

 The  lack of the receptor was particularly common in patients who had to be treated with Covid-19 in intensive care units, regardless of age or gender. Genetic variations in the HLA-E of the infected cell were also associated with the severity of the disease, albeit to a lesser extent, ”explained Puchhammer-Stöckl. © www.de24.news

 The  current study, which recently appeared in the journal “Genetics in Medicine”, therefore shows the great importance of the NK cell response in the fight against SARS-CoV-2 infection.

(aeg / sda / apa)

THANK YOU FOR THE ♥

Would you like to support watson and journalism? Learn more

(You will be redirected to complete the payment)

5 CHF

15 CHF

25 CHF

Another

© www.de24.news

 The  coronavirus in Switzerland – a chronology

World of watson: Päärli-Lockdown – der Film

You might also be interested in:

Subscribe to our newsletter

WhatsApp will soon show users banners in chat: that’s behind it

WhatsApp users have until mid-May to agree to the new guidelines. Until then, the messenger wants to do educational work – in the app itself.

WhatsApp plans to introduce a banner to users in the coming weeks, which will be visible at the top of the “Chat” tab. © www.de24.news

 The  banner is intended to give users the opportunity to take a closer look at the new terms of use. WhatsApp writes in a press release.

© www.de24.news

 The  reason for this action is the announcement by WhatsApp to adapt its terms of use. Because with the new guidelines, the messenger should be allowed to share personal data with Facebook in the future. That ensured …

Link to the article





[ source link ]
https://www.watson.ch/wissen/coronavirus/408203722-was-entscheidet-ob-ein-corona-verlauf-schlimm-wird

decides corona bad

LEAVE A REPLY

Please enter your comment!
Please enter your name here